Women are more prone to Lupus. Statistics show that women are eight times more susceptible to the disease than men. In most cases, disease appears between 15 and 45 years. Women having Lupus might experience complications during pregnancy, but it will not reduce fertility. Miscarriage, premature delivery, sudden increase in blood pressure, etc. are the risk factors experienced by 50 percent of pregnant women diagnosed with the disease. However, proper medication can help control complications and symptoms. Growth of the baby should be checked including kidney and liver functions. For the successful management of the Lupus during pregnancy, a multi-disciplinary approach is a must.